Transcellular transport of lipoprotein through arterial endothelial cells in monolayer culture.
نویسندگان
چکیده
منابع مشابه
Transport of lipoprotein lipase across endothelial cells.
Lipoprotein lipase (LPL), synthesized in muscle and fat, hydrolyzes plasma triglycerides primarily while bound to luminal endothelial cell surfaces. To obtain information about the movement of LPL from the basal to the luminal endothelial cell surface, we studied the transport of purified bovine milk LPL across bovine aortic endothelial cell monolayers. 125I-labeled LPL (125I-LPL) added to the ...
متن کاملBinding of lipoprotein lipase to endothelial cells in culture.
Equilibrium-binding data of highly purified avian lipoprotein lipase to cultured bovine endothelial cells demonstrate the presence of a class of high affinity sites. Analysis of the binding function by weighted least squares technique yielded an association constant of K = 0.7 X 10(7) M-1 and a maximum binding capacity of 1.6 micrograms/1.9 X 10(6) cells. Lipoprotein lipase was monitored both b...
متن کاملEnhancement of calcium transport in Caco-2 monolayer through PKCzeta-dependent Cav1.3-mediated transcellular and rectifying paracellular pathways by prolactin.
Previous investigations suggested that prolactin (PRL) stimulated the intestinal calcium absorption through phosphoinositide 3-kinase (PI3K), protein kinase C (PKC), and RhoA-associated coiled-coil forming kinase (ROCK) signaling pathways. However, little was known regarding its detailed mechanisms for the stimulation of transcellular and voltage-dependent paracellular calcium transport. By usi...
متن کاملEnhancement of calcium transport in Caco-2 monolayer through PKC - dependent Cav1.3-mediated transcellular and rectifying paracellular pathways by prolactin
Thongon N, Nakkrasae L, Thongbunchoo J, Krishnamra N, Charoenphandhu N. Enhancement of calcium transport in Caco-2 monolayer through PKC -dependent Cav1.3-mediated transcellular and rectifying paracellular pathways by prolactin. Am J Physiol Cell Physiol 296: C1373–C1382, 2009. First published April 1, 2009; doi:10.1152/ajpcell.00053.2009.—Previous investigations suggested that prolactin (PRL) ...
متن کاملTranscellular Pathways in Lymphatic Endothelial Cells Regulate Changes in Solute Transport by Fluid Stress.
RATIONALE The transport of interstitial fluid and solutes into lymphatic vessels is important for maintaining interstitial homeostasis and delivering antigens and soluble factors to the lymph node for immune surveillance. Transendothelial transport across lymphatic endothelial cells (LECs) is commonly considered to occur paracellularly, or between cell-cell junctions, and driven by local pressu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Structure and Function
سال: 1986
ISSN: 0386-7196,1347-3700
DOI: 10.1247/csf.11.31